Radiation nephritis following combined abdominal radiation and chemotherapy (bleomycin-vinblastine)
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چکیده
منابع مشابه
Radiation nephritis.
Radiation nephritis has not had wide attention in the medical literature. Maniy physicians have erroneously considered the kidney to be resistant to the effects of irradiation. This illusion is partly due to the fact that the clinical signs of renal impairment are often subtle and therefore overlooked, or are mistakenly attributed to the primary condition for which radiotherapy was given. Furth...
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In an attempt to develop better combination therapies for use with local radiation, the interaction between bleomycin and hyperthermia +/- radiation was studied in the FSaIIC tumor system. In cells exposed in vitro to bleomycin at 37 degrees C and at pH 7.40, the drug was substantially more toxic toward normally oxygenated than hypoxic cells. At hyperthermic temperatures (42 degrees or 43 degre...
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Introduction Adjuvant chemotherapy is now being employed in the management of several solid tumour malignancies in an attempt to improve prognosis. It is based on the concept that chemotherapy has the greatest chance of eliminating the disease when the tumour cell mass is minimal, and therefore, it is argued that if chemotherapy be employed at a stage when metastases are likely to be present, b...
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Radiation nephritis is both volume and dose related. Clinical experience would indicate that a minimum of one third of the renal volume needs to be excluded from nephrotoxic doses which appears to have a threshold of 2,000 cGy. The site of damage leading to renal failure appears to be the microvasculature ultimately expressed as glomerulosclerosis. How much direct damage to the tubular system c...
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Interdigitating dendritic cell sarcoma (IDCS) is a very rare and aggressive neoplasm that arises from antigen presenting cells. IDCS usually involves lymph nodes; however, extra-nodal involvement has also been reported. Because a consistent standard therapy for IDCS has not been established to date, we report a case of the successful treatment of disseminated IDCS using ABVD chemotherapy (doxor...
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ژورنال
عنوان ژورنال: Cancer
سال: 1978
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(197806)41:6<2162::aid-cncr2820410614>3.0.co;2-z